Cleft Palate, Moderate Lung Developmental Retardation and Early Postnatal Lethality in Mice Deficient in the Kir7.1 Inwardly Rectifying K(+) Channel

Kir7.1 is an inwardly rectifying K(+) channel of the Kir superfamily encoded by the kcnj13 gene. Kir7.1 is present in epithelial tissues where it colocalizes with the Na(+)/K(+)-pump probably serving to recycle K(+) taken up by the pump. Human mutations affecting Kir7.1 are associated with retinal d...

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Detalles Bibliográficos
Autores principales: Villanueva, Sandra, Burgos, Johanna, López-Cayuqueo, Karen I., Lai, Ka-Man Venus, Valenzuela, David M., Cid, L. Pablo, Sepúlveda, Francisco V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4581704/
https://www.ncbi.nlm.nih.gov/pubmed/26402555
http://dx.doi.org/10.1371/journal.pone.0139284

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4581704/
https://www.ncbi.nlm.nih.gov/pubmed/26402555
http://dx.doi.org/10.1371/journal.pone.0139284

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