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Discovering Genetic Interactions in Large-Scale Association Studies by Stage-wise Likelihood Ratio Tests

Despite the success of genome-wide association studies in medical genetics, the underlying genetics of many complex diseases remains enigmatic. One plausible reason for this could be the failure to account for the presence of genetic interactions in current analyses. Exhaustive investigations of int...

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Detalles Bibliográficos
Autores principales: Frånberg, Mattias, Gertow, Karl, Hamsten, Anders, Lagergren, Jens, Sennblad, Bengt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4581725/
https://www.ncbi.nlm.nih.gov/pubmed/26402789
http://dx.doi.org/10.1371/journal.pgen.1005502