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Discovering Genetic Interactions in Large-Scale Association Studies by Stage-wise Likelihood Ratio Tests
Despite the success of genome-wide association studies in medical genetics, the underlying genetics of many complex diseases remains enigmatic. One plausible reason for this could be the failure to account for the presence of genetic interactions in current analyses. Exhaustive investigations of int...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4581725/ https://www.ncbi.nlm.nih.gov/pubmed/26402789 http://dx.doi.org/10.1371/journal.pgen.1005502 |