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Experimental Malaria in Pregnancy Induces Neurocognitive Injury in Uninfected Offspring via a C5a-C5a Receptor Dependent Pathway

The in utero environment profoundly impacts childhood neurodevelopment and behaviour. A substantial proportion of pregnancies in Africa are at risk of malaria in pregnancy (MIP) however the impact of in utero exposure to MIP on fetal neurodevelopment is unknown. Complement activation, in particular...

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Detalles Bibliográficos
Autores principales: McDonald, Chloë R., Cahill, Lindsay S., Ho, Keith T., Yang, Jimmy, Kim, Hani, Silver, Karlee L., Ward, Peter A., Mount, Howard T., Liles, W. Conrad, Sled, John G., Kain, Kevin C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4581732/
https://www.ncbi.nlm.nih.gov/pubmed/26402732
http://dx.doi.org/10.1371/journal.ppat.1005140