Extract of Rhizoma Polygonum cuspidatum reduces early renal podocyte injury in streptozotocin-induced diabetic rats and its active compound emodin inhibits methylglyoxal-mediated glycation of proteins

Podocyte injury contributes to renal damage and, eventually, to the occurrence of proteinuria in diabetic nephropathy. The aim of the present study was to investigate the effect of an ethanol extract from Rhizoma Polygonum cuspidatum (P. cuspidatum) on proteinuria and podocyte injury, and elucidate...

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Detalles Bibliográficos
Autores principales: SOHN, EUNJIN, KIM, JUNGHYUN, KIM, CHAN SIK, JO, KYUHYUNG, KIM, JIN SOOK
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4581740/
https://www.ncbi.nlm.nih.gov/pubmed/26299942
http://dx.doi.org/10.3892/mmr.2015.4214

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4581740/
https://www.ncbi.nlm.nih.gov/pubmed/26299942
http://dx.doi.org/10.3892/mmr.2015.4214

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