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Molecular docking to explore the possible binding mode of potential inhibitors of thioredoxin glutathione reductase
Praziquantel (PZQ) is the treatment of choice for schistosomiasis, one of the most important but neglected tropical diseases. Recently, however, Schistosoma have exhibited reduced susceptibility to PZQ, and an urgent need to develop new drugs to treat schistosomiasis has emerged. Thioredoxin glutath...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4581810/ https://www.ncbi.nlm.nih.gov/pubmed/26239395 http://dx.doi.org/10.3892/mmr.2015.4119 |