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Molecular docking to explore the possible binding mode of potential inhibitors of thioredoxin glutathione reductase

Praziquantel (PZQ) is the treatment of choice for schistosomiasis, one of the most important but neglected tropical diseases. Recently, however, Schistosoma have exhibited reduced susceptibility to PZQ, and an urgent need to develop new drugs to treat schistosomiasis has emerged. Thioredoxin glutath...

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Detalles Bibliográficos
Autores principales: HUANG, JINGWEI, HUA, WEIJUAN, LI, JIAHUANG, HUA, ZICHUN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4581810/
https://www.ncbi.nlm.nih.gov/pubmed/26239395
http://dx.doi.org/10.3892/mmr.2015.4119