Structural analysis of a type 1 ribosome inactivating protein reveals multiple L-asparagine-N-acetyl-D-glucosamine monosaccharide modifications: Implications for cytotoxicity

Pokeweed antiviral protein (PAP) belongs to the family of type I ribosome-inactivating proteins (RIPs): Ribotoxins, which function by depurinating the sarcin-ricin loop of ribosomal RNA. In addition to its antibacterial and antifungal properties, PAP has shown promise in antiviral and targeted tumor...

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Detalles Bibliográficos
Autores principales: HOGG, TANIS, MENDEL, JAMESON T., LAVEZO, JONATHAN L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4581812/
https://www.ncbi.nlm.nih.gov/pubmed/26238506
http://dx.doi.org/10.3892/mmr.2015.4146

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4581812/
https://www.ncbi.nlm.nih.gov/pubmed/26238506
http://dx.doi.org/10.3892/mmr.2015.4146

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