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Structure-Activity Relationship of Indole-Tethered Pyrimidine Derivatives that Concurrently Inhibit Epidermal Growth Factor Receptor and Other Angiokinases

Antiangiogenic agents have been widely investigated in combination with standard chemotherapy or targeted cancer agents for better management of advanced cancers. Therapeutic agents that concurrently inhibit epidermal growth factor receptor and other angiokinases could be useful alternatives to comb...

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Detalles Bibliográficos
Autores principales: Song, Jiho, Yoo, Jakyung, Kwon, Ara, Kim, Doran, Nguyen, Hong Khanh, Lee, Bong-Yong, Suh, Wonhee, Min, Kyung Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4581874/
https://www.ncbi.nlm.nih.gov/pubmed/26401847
http://dx.doi.org/10.1371/journal.pone.0138823