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Kinetics of drug action in disease states: towards physiology-based pharmacodynamic (PBPD) models
Gerhard Levy started his investigations on the “Kinetics of Drug Action in Disease States” in the fall of 1980. The objective of his research was to study inter-individual variation in pharmacodynamics. To this end, theoretical concepts and experimental approaches were introduced, which enabled asse...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Springer US
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4582079/ https://www.ncbi.nlm.nih.gov/pubmed/26319673 http://dx.doi.org/10.1007/s10928-015-9437-x |