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Sex-specific dysregulation of cysteine oxidation and the methionine and folate cycles in female cystathionine gamma-lyase null mice: a serendipitous model of the methylfolate trap

In addition to its role in the endogenous synthesis of cysteine, cystathionine gamma-lyase (CGL) is a major physiological source of the vasorelaxant hydrogen sulfide. Cgl null mice are potentially useful for studying the influence of this compound upon vascular tone and endothelial function. Here, w...

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Detalles Bibliográficos
Autores principales: Jiang, Hua, Hurt, K. Joseph, Breen, Kelsey, Stabler, Sally P., Allen, Robert H., Orlicky, David J., Maclean, Kenneth N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4582125/
https://www.ncbi.nlm.nih.gov/pubmed/26276101
http://dx.doi.org/10.1242/bio.013433