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Chemical perturbation of an intrinsically disordered region of TFIID distinguishes two modes of transcription initiation

Intrinsically disordered proteins/regions (IDPs/IDRs) are proteins or peptide segments that fail to form stable 3-dimensional structures in the absence of partner proteins. They are abundant in eukaryotic proteomes and are often associated with human diseases, but their biological functions have bee...

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Detalles Bibliográficos
Autores principales: Zhang, Zhengjian, Boskovic, Zarko, Hussain, Mahmud M, Hu, Wenxin, Inouye, Carla, Kim, Han-Je, Abole, A Katherine, Doud, Mary K, Lewis, Timothy A, Koehler, Angela N, Schreiber, Stuart L, Tjian, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4582147/
https://www.ncbi.nlm.nih.gov/pubmed/26314865
http://dx.doi.org/10.7554/eLife.07777