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Adapted Resistance to the Knockdown Effect of shRNA-Derived Srsf3 siRNAs in Mouse Littermates

Gene silencing techniques are widely used to control gene expression and have potential for RNAi-based therapeutics. In this report, transgenic mouse lines were created for conditional knockdown of Srsf3 (SRp20) expression in liver and mammary gland tissues by expressing Srsf3-specific shRNAs driven...

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Detalles Bibliográficos
Autores principales: Ajiro, Masahiko, Jia, Rong, Wang, Rui-Hong, Deng, Chu-Xia, Zheng, Zhi-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4582148/
https://www.ncbi.nlm.nih.gov/pubmed/26435690
http://dx.doi.org/10.7150/ijbs.13011