NF-κB-DICER-miRs Axis Regulates TNF-α Expression in Responses to Endotoxin Stress

Unbalanced tumor necrosis factor (TNF)-α production is associated with pathogenesis of a variety of human diseases. However, the molecular pathways maintaining TNF-α homeostasis remain elusive. Here, we report that NF-κB/p65-DICER-miRs axis negatively regulates TNF-α production. We demonstrated that...

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Detalles Bibliográficos
Autores principales: Guan, Yi, Yao, Hailan, Wang, Junfeng, Sun, Kailai, Cao, Liu, Wang, Yizheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4582149/
https://www.ncbi.nlm.nih.gov/pubmed/26435691
http://dx.doi.org/10.7150/ijbs.12611

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4582149/
https://www.ncbi.nlm.nih.gov/pubmed/26435691
http://dx.doi.org/10.7150/ijbs.12611

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