Cargando…
NF-κB-DICER-miRs Axis Regulates TNF-α Expression in Responses to Endotoxin Stress
Unbalanced tumor necrosis factor (TNF)-α production is associated with pathogenesis of a variety of human diseases. However, the molecular pathways maintaining TNF-α homeostasis remain elusive. Here, we report that NF-κB/p65-DICER-miRs axis negatively regulates TNF-α production. We demonstrated that...
Autores principales: | Guan, Yi, Yao, Hailan, Wang, Junfeng, Sun, Kailai, Cao, Liu, Wang, Yizheng |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4582149/ https://www.ncbi.nlm.nih.gov/pubmed/26435691 http://dx.doi.org/10.7150/ijbs.12611 |
Ejemplares similares
-
NF-κB-modulated miR-130a targets TNF-α in cervical cancer cells
por: Zhang, Jian, et al.
Publicado: (2014) -
Mechanism of Probiotic VSL#3 Inhibiting NF-κB and TNF-α on Colitis through TLR4-NF-κB Signal Pathway
por: WANG, Hui, et al.
Publicado: (2019) -
Nimbolide protects against endotoxin-induced acute respiratory distress syndrome by inhibiting TNF-α mediated NF-κB and HDAC-3 nuclear translocation
por: Pooladanda, Venkatesh, et al.
Publicado: (2019) -
ATM-NFκB axis-driven TIGAR regulates sensitivity of glioma cells to radiomimetics in the presence of TNFα
por: Sinha, S, et al.
Publicado: (2013) -
MCPIP1 Enhances TNF-α-Mediated Apoptosis through Downregulation of the NF-κB/cFLIP Axis
por: Suk, Fat-Moon, et al.
Publicado: (2021)