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Yap and Taz regulate retinal pigment epithelial cell fate

The optic vesicle comprises a pool of bi-potential progenitor cells from which the retinal pigment epithelium (RPE) and neural retina fates segregate during ocular morphogenesis. Several transcription factors and signaling pathways have been shown to be important for RPE maintenance and differentiat...

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Detalles Bibliográficos
Autores principales: Miesfeld, Joel B., Gestri, Gaia, Clark, Brian S., Flinn, Michael A., Poole, Richard J., Bader, Jason R., Besharse, Joseph C., Wilson, Stephen W., Link, Brian A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4582179/
https://www.ncbi.nlm.nih.gov/pubmed/26209646
http://dx.doi.org/10.1242/dev.119008