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Yap and Taz regulate retinal pigment epithelial cell fate
The optic vesicle comprises a pool of bi-potential progenitor cells from which the retinal pigment epithelium (RPE) and neural retina fates segregate during ocular morphogenesis. Several transcription factors and signaling pathways have been shown to be important for RPE maintenance and differentiat...
Autores principales: | Miesfeld, Joel B., Gestri, Gaia, Clark, Brian S., Flinn, Michael A., Poole, Richard J., Bader, Jason R., Besharse, Joseph C., Wilson, Stephen W., Link, Brian A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4582179/ https://www.ncbi.nlm.nih.gov/pubmed/26209646 http://dx.doi.org/10.1242/dev.119008 |
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