Binding of SGTA to Rpn13 selectively modulates protein quality control

Rpn13 is an intrinsic ubiquitin receptor of the 26S proteasome regulatory subunit that facilitates substrate capture prior to degradation. Here we show that the C-terminal region of Rpn13 binds to the tetratricopeptide repeat (TPR) domain of SGTA, a cytosolic factor implicated in the quality control...

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Detalles Bibliográficos
Autores principales: Leznicki, Pawel, Korac-Prlic, Jelena, Kliza, Katarzyna, Husnjak, Koraljka, Nyathi, Yvonne, Dikic, Ivan, High, Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4582187/
https://www.ncbi.nlm.nih.gov/pubmed/26169395
http://dx.doi.org/10.1242/jcs.165209

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4582187/
https://www.ncbi.nlm.nih.gov/pubmed/26169395
http://dx.doi.org/10.1242/jcs.165209

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