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Structural dynamics of E. coli single-stranded DNA binding protein reveal DNA wrapping and unwrapping pathways

Escherichia coli single-stranded (ss)DNA binding (SSB) protein mediates genome maintenance processes by regulating access to ssDNA. This homotetrameric protein wraps ssDNA in multiple distinct binding modes that may be used selectively in different DNA processes, and whose detailed wrapping topologi...

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Detalles Bibliográficos
Autores principales: Suksombat, Sukrit, Khafizov, Rustem, Kozlov, Alexander G, Lohman, Timothy M, Chemla, Yann R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4582245/
https://www.ncbi.nlm.nih.gov/pubmed/26305498
http://dx.doi.org/10.7554/eLife.08193