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Refining multivariate disease phenotypes for high chip heritability

BACKGROUND: Statistical genetics shows that the success of both genetic association studies and genomic prediction methods is positively associated with the heritability of the trait used in the analysis. Identifying highly heritable components of a complex disease can thus enhance genetic studies o...

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Detalles Bibliográficos
Autores principales: Sun, Jiangwen, Kranzler, Henry R, Bi, Jinbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4582350/
https://www.ncbi.nlm.nih.gov/pubmed/26399736
http://dx.doi.org/10.1186/1755-8794-8-S3-S3