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C9ORF72 expression and cellular localization over mouse development

INTRODUCTION: A majority of familial frontotemporal lobar dementia and amyotrophic lateral sclerosis cases are associated with a large repeat expansion in a non-coding region of the C9ORF72 gene. Currently, little is known about the normal function and the expression pattern of the C9ORF72 protein....

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Detalles Bibliográficos
Autores principales: Atkinson, Rachel A K, Fernandez-Martos, Carmen M., Atkin, Julie D., Vickers, James C., King, Anna E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4582620/
https://www.ncbi.nlm.nih.gov/pubmed/26408000
http://dx.doi.org/10.1186/s40478-015-0238-7