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Navβ4 regulates fast resurgent sodium currents and excitability in sensory neurons

BACKGROUND: Increased electrical activity in peripheral sensory neurons including dorsal root ganglia (DRG) and trigeminal ganglia neurons is an important mechanism underlying pain. Voltage gated sodium channels (VGSC) contribute to the excitability of sensory neurons and are essential for the upstr...

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Detalles Bibliográficos
Autores principales: Barbosa, Cindy, Tan, Zhi-Yong, Wang, Ruizhong, Xie, Wenrui, Strong, Judith A., Patel, Reesha R., Vasko, Michael R., Zhang, Jun-Ming, Cummins, Theodore R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4582632/
https://www.ncbi.nlm.nih.gov/pubmed/26408173
http://dx.doi.org/10.1186/s12990-015-0063-9