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Navβ4 regulates fast resurgent sodium currents and excitability in sensory neurons
BACKGROUND: Increased electrical activity in peripheral sensory neurons including dorsal root ganglia (DRG) and trigeminal ganglia neurons is an important mechanism underlying pain. Voltage gated sodium channels (VGSC) contribute to the excitability of sensory neurons and are essential for the upstr...
Autores principales: | Barbosa, Cindy, Tan, Zhi-Yong, Wang, Ruizhong, Xie, Wenrui, Strong, Judith A., Patel, Reesha R., Vasko, Michael R., Zhang, Jun-Ming, Cummins, Theodore R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4582632/ https://www.ncbi.nlm.nih.gov/pubmed/26408173 http://dx.doi.org/10.1186/s12990-015-0063-9 |
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