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In vitro effects of 3 % hypertonic saline and 20 % mannitol on canine whole blood coagulation and platelet function

BACKGROUND: Hyperosmolar therapy, using either mannitol or hypertonic saline (HTS), is considered the treatment of choice for intracranial hypertension. However, hyperosmolar agents may impair coagulation and platelet function, limiting their use in patients at risk for hemorrhage. Despite this, stu...

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Detalles Bibliográficos
Autores principales: Adamik, Katja-Nicole, Butty, Emmanuelle, Howard, Judith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4582639/
https://www.ncbi.nlm.nih.gov/pubmed/26403081
http://dx.doi.org/10.1186/s12917-015-0555-x