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Copper-free click chemistry for attachment of biomolecules in magnetic tweezers

BACKGROUND: Single-molecule techniques have proven to be an excellent approach for quantitatively studying DNA-protein interactions at the single-molecule level. In magnetic tweezers, a force is applied to a biopolymer that is anchored between a glass surface and a magnetic bead. Whereas the relevan...

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Detalles Bibliográficos
Autores principales: Eeftens, Jorine M., van der Torre, Jaco, Burnham, Daniel R., Dekker, Cees
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4582843/
https://www.ncbi.nlm.nih.gov/pubmed/26413268
http://dx.doi.org/10.1186/s13628-015-0023-9