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Shikonin-enhanced cell immunogenicity of tumor vaccine is mediated by the differential effects of DAMP components

BACKGROUND: The tumor cell lysate-pulsed, dendritic cell (DC)-based cancer vaccine approaches are being actively evaluated for application to cancer immunotherapy, hopefully at a personalized medicine base. There is apparently an emerging technical problem however, the lack of highly efficacious pot...

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Detalles Bibliográficos
Autores principales: Lin, Tien-Jen, Lin, Hsin-Ting, Chang, Wei-Ting, Mitapalli. S, Pradeep, Hsiao, Pei-Wen, Yin, Shu-Yi, Yang, Ning-Sun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4582891/
https://www.ncbi.nlm.nih.gov/pubmed/26403780
http://dx.doi.org/10.1186/s12943-015-0435-9