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Pharmacogenomic study in patients with multiple sclerosis: Responders and nonresponders to IFN-β

OBJECTIVES: We aimed to investigate the association between polymorphisms located in type I interferon (IFN)-induced genes, genes belonging to the toll-like receptor (TLR) pathway, and genes encoding neurotransmitter receptors and the response to IFN-β treatment in patients with multiple sclerosis (...

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Detalles Bibliográficos
Autores principales: Bustamante, Marta F., Morcillo-Suárez, Carlos, Malhotra, Sunny, Rio, Jordi, Leyva, Laura, Fernández, Oscar, Zettl, Uwe K., Killestein, Joep, Brassat, David, García-Merino, Juan Antonio, Sánchez, Antonio J., Urcelay, Elena, Alvarez-Lafuente, Roberto, Villar, Lusia M., Alvarez-Cermeño, Jose Carlos, Farré, Xavier, Lechner-Scott, Jeannette, Vandenbroeck, Koen, Rodríguez-Antigüedad, Alfredo, Drulovic, Jelena S., Martinelli Boneschi, Filippo, Chan, Andrew, Oksenberg, Jorge, Navarro, Arcadi, Montalban, Xavier, Comabella, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4582905/
https://www.ncbi.nlm.nih.gov/pubmed/26445728
http://dx.doi.org/10.1212/NXI.0000000000000154