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Role of Type 1 Diabetes–Associated SNPs on Autoantibody Positivity in the Type 1 Diabetes Genetics Consortium: Overview

OBJECTIVE: Type 1 diabetes (T1D) arises from the autoimmune destruction of the β-cells of the pancreas, resulting in dependence on exogenously administered insulin for survival. Key biomarkers of the autoimmune process in T1D are the occurrence of autoantibodies directed against β-cells and other an...

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Detalles Bibliográficos
Autores principales: Rich, Stephen S., Concannon, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4582912/
https://www.ncbi.nlm.nih.gov/pubmed/26405066
http://dx.doi.org/10.2337/dcs15-2001