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Targeted therapies to improve CFTR function in cystic fibrosis

Cystic fibrosis is the most common genetically determined, life-limiting disorder in populations of European ancestry. The genetic basis of cystic fibrosis is well established to be mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene that codes for an apical membrane chl...

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Detalles Bibliográficos
Autores principales: Brodlie, Malcolm, Haq, Iram J., Roberts, Katie, Elborn, J. Stuart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4582929/
https://www.ncbi.nlm.nih.gov/pubmed/26403534
http://dx.doi.org/10.1186/s13073-015-0223-6