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Paramagnetic Ligand Tagging To Identify Protein Binding Sites
[Image: see text] Transient biomolecular interactions are the cornerstones of the cellular machinery. The identification of the binding sites for low affinity molecular encounters is essential for the development of high affinity pharmaceuticals from weakly binding leads but is hindered by the lack...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4583072/ https://www.ncbi.nlm.nih.gov/pubmed/26289584 http://dx.doi.org/10.1021/jacs.5b06220 |