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Paramagnetic Ligand Tagging To Identify Protein Binding Sites

[Image: see text] Transient biomolecular interactions are the cornerstones of the cellular machinery. The identification of the binding sites for low affinity molecular encounters is essential for the development of high affinity pharmaceuticals from weakly binding leads but is hindered by the lack...

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Detalles Bibliográficos
Autores principales: Brath, Ulrika, Swamy, Shashikala I., Veiga, Alberte X., Tung, Ching-Chieh, Van Petegem, Filip, Erdélyi, Máté
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2015
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4583072/
https://www.ncbi.nlm.nih.gov/pubmed/26289584
http://dx.doi.org/10.1021/jacs.5b06220