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TRX-LOGOS - a graphical tool to demonstrate DNA information content dependent upon backbone dynamics in addition to base sequence
BACKGROUND: It is now widely-accepted that DNA sequences defining DNA-protein interactions functionally depend upon local biophysical features of DNA backbone that are important in defining sites of binding interaction in the genome (e.g. DNA shape, charge and intrinsic dynamics). However, these phy...
Autores principales: | Fortin, Connor H., Schulze, Katharina V., Babbitt, Gregory A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4583169/ https://www.ncbi.nlm.nih.gov/pubmed/26413153 http://dx.doi.org/10.1186/s13029-015-0040-8 |
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