Significant improvement of oxidase activity through the genetic incorporation of a redox-active unnatural amino acid

While nature employs various covalent and non-covalent strategies to modulate tyrosine (Y) redox potential and pK (a) in order to optimize enzyme activities, such approaches have not been systematically applied for the design of functional metalloproteins. Through the genetic incorporation of 3-meth...

Descripción completa

Detalles Bibliográficos
Autores principales: Yu, Yang, Zhou, Qing, Wang, Li, Liu, Xiaohong, Zhang, Wei, Hu, Meirong, Dong, Jianshu, Li, Jiasong, Lv, Xiaoxuan, Ouyang, Hanlin, Li, Han, Gao, Feng, Gong, Weimin, Lu, Yi, Wang, Jiangyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2015
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4583198/
https://www.ncbi.nlm.nih.gov/pubmed/26417427
http://dx.doi.org/10.1039/c5sc01126d

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4583198/
https://www.ncbi.nlm.nih.gov/pubmed/26417427
http://dx.doi.org/10.1039/c5sc01126d

Ejemplares similares