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TAT Modification of Alpha-Helical Anticancer Peptides to Improve Specificity and Efficacy

HPRP-A1 is an amphipathic α-helical anticancer peptide (ACP) derived from the N-terminus of ribosomal protein L1 (RpL1) of Helicobacter pylori. In our previously study, HPRP-A1 has been reported that induced HeLa cell apoptosis in a caspase-dependent approach and involved both by the death receptor...

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Detalles Bibliográficos
Autores principales: Hao, Xueyu, Yan, Qiuyan, Zhao, Jing, Wang, Wenren, Huang, Yibing, Chen, Yuxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4583266/
https://www.ncbi.nlm.nih.gov/pubmed/26405806
http://dx.doi.org/10.1371/journal.pone.0138911