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Histone H1 Differentially Inhibits DNA Bending by Reduced and Oxidized HMGB1 Protein

HMGB1 protein and linker histone H1 have overlapping binding sites in the nucleosome. HMGB1 has been implicated in many DNA-dependent processes in chromatin involving binding of specific proteins, including transcription factors, to DNA sites pre-bent by HMGB1. HMGB1 can also act as an extracellular...

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Detalles Bibliográficos
Autores principales: Štros, Michal, Polanská, Eva, Kučírek, Martin, Pospíšilová, Šárka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4583294/
https://www.ncbi.nlm.nih.gov/pubmed/26406975
http://dx.doi.org/10.1371/journal.pone.0138774