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Inhibition of Mitochondrial Complex I Leads to Decreased Motility and Membrane Integrity Related to Increased Hydrogen Peroxide and Reduced ATP Production, while the Inhibition of Glycolysis Has Less Impact on Sperm Motility

Mitochondria have been proposed as the major source of reactive oxygen species in somatic cells and human spermatozoa. However, no data regarding the role of mitochondrial ROS production in stallion spermatozoa are available. To shed light on the role of the mitochondrial electron transport chain in...

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Detalles Bibliográficos
Autores principales: Plaza Davila, María, Martin Muñoz, Patricia, Tapia, Jose A., Ortega Ferrusola, Cristina, Balao da Silva C, Carolina, Peña, Fernando J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4583303/
https://www.ncbi.nlm.nih.gov/pubmed/26407142
http://dx.doi.org/10.1371/journal.pone.0138777