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Antibodies Targeting Novel Neutralizing Epitopes of Hepatitis C Virus Glycoprotein Preclude Genotype 2 Virus Infection

Currently, there is no effective vaccine to prevent hepatitis C virus (HCV) infection, partly due to our insufficient understanding of the virus glycoprotein immunology. Most neutralizing antibodies (nAbs) were identified using glycoprotein immunogens, such as recombinant E1E2, HCV pseudoparticles o...

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Detalles Bibliográficos
Autores principales: Deng, Kai, Liu, Ruyu, Rao, Huiying, Jiang, Dong, Wang, Jianghua, Xie, Xingwang, Wei, Lai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4583415/
https://www.ncbi.nlm.nih.gov/pubmed/26406225
http://dx.doi.org/10.1371/journal.pone.0138756