The Deacetylase Sirtuin 1 Regulates Human Papillomavirus Replication by Modulating Histone Acetylation and Recruitment of DNA Damage Factors NBS1 and Rad51 to Viral Genomes

Human papillomaviruses (HPV) regulate their differentiation-dependent life cycles by activating a number of cellular pathways, such as the DNA damage response, through control of post-translational protein modification. Sirtuin 1 (SIRT1) is a protein deacetylase that modulates the acetylation of a n...

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Detalles Bibliográficos
Autores principales: Langsfeld, Erika S., Bodily, Jason M., Laimins, Laimonis A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4583417/
https://www.ncbi.nlm.nih.gov/pubmed/26405826
http://dx.doi.org/10.1371/journal.ppat.1005181

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4583417/
https://www.ncbi.nlm.nih.gov/pubmed/26405826
http://dx.doi.org/10.1371/journal.ppat.1005181

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