msCentipede: Modeling Heterogeneity across Genomic Sites and Replicates Improves Accuracy in the Inference of Transcription Factor Binding

Understanding global gene regulation depends critically on accurate annotation of regulatory elements that are functional in a given cell type. CENTIPEDE, a powerful, probabilistic framework for identifying transcription factor binding sites from tissue-specific DNase I cleavage patterns and genomic...

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Detalles Bibliográficos
Autores principales: Raj, Anil, Shim, Heejung, Gilad, Yoav, Pritchard, Jonathan K., Stephens, Matthew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4583425/
https://www.ncbi.nlm.nih.gov/pubmed/26406244
http://dx.doi.org/10.1371/journal.pone.0138030

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4583425/
https://www.ncbi.nlm.nih.gov/pubmed/26406244
http://dx.doi.org/10.1371/journal.pone.0138030

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