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Rapid Myoglobin Aggregation through Glucosamine-Induced α-Dicarbonyl Formation

The extent of glycation and conformational changes of horse myoglobin (Mb) upon glycation with N-acetyl-glucosamine (GlcNAc), glucose (Glc) and glucosamine (GlcN) were investigated. Among tested sugars, the rate of glycation with GlcN was the most rapid as shown by MALDI and ESI mass spectrometries....

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Detalles Bibliográficos
Autores principales: Hrynets, Yuliya, Ndagijimana, Maurice, Betti, Mirko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4583429/
https://www.ncbi.nlm.nih.gov/pubmed/26406447
http://dx.doi.org/10.1371/journal.pone.0139022