Aptamer-Dendrimer Bioconjugates for Targeted Delivery of miR-34a Expressing Plasmid and Antitumor Effects in Non-Small Cell Lung Cancer Cells

Metastasis and drug resistance are major barriers for the treatment of non-small cell lung cancer (NSCLC). To explore new therapeutic options, we successfully encapsulated MicroRNA-34a (miR-34a), a potent endogenous tumor suppressor in NSCLC into S6 aptamer-conjugated dendrimer to form lung cancer-t...

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Detalles Bibliográficos
Autores principales: Wang, Hongmei, Zhao, Xin, Guo, Caihong, Ren, Dunqiang, Zhao, Yandong, Xiao, Wei, Jiao, Wenjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4583438/
https://www.ncbi.nlm.nih.gov/pubmed/26406332
http://dx.doi.org/10.1371/journal.pone.0139136

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4583438/
https://www.ncbi.nlm.nih.gov/pubmed/26406332
http://dx.doi.org/10.1371/journal.pone.0139136

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