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A Multiple siRNA-Based Anti-HIV/SHIV Microbicide Shows Protection in Both In Vitro and In Vivo Models

Human immunodeficiency virus (HIV) types 1 and 2 (HIV-1 and HIV-2) are the etiologic agents of AIDS. Most HIV-1 infected individuals worldwide are women, who acquire HIV infections during sexual contact. Blocking HIV mucosal transmission and local spread in the female lower genital tract is importan...

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Detalles Bibliográficos
Autores principales: Boyapalle, Sandhya, Xu, Weidong, Raulji, Payal, Mohapatra, Subhra, Mohapatra, Shyam S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4583459/
https://www.ncbi.nlm.nih.gov/pubmed/26407080
http://dx.doi.org/10.1371/journal.pone.0135288