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Electrophysiological Studies into the Safety of the Anti-diarrheal Drug Clotrimazole during Oral Rehydration Therapy

BACKGROUND AND AIMS: Morbidity and mortality from acute diarrheal disease remains high, particularly in developing countries and in cases of natural or man-made disasters. Previous work has shown that the small molecule clotrimazole inhibits intestinal Cl(-) secretion by blocking both cyclic nucleot...

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Detalles Bibliográficos
Autores principales: Lexmond, Willem S., Rufo, Paul A., Fiebiger, Edda, Lencer, Wayne I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4583490/
https://www.ncbi.nlm.nih.gov/pubmed/26405813
http://dx.doi.org/10.1371/journal.pntd.0004098