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Generation and Characterization of Live Attenuated Influenza A(H7N9) Candidate Vaccine Virus Based on Russian Donor of Attenuation

BACKGROUND: Avian influenza A (H7N9) virus has emerged recently and continues to cause severe disease with a high mortality rate in humans prompting the development of candidate vaccine viruses. Live attenuated influenza vaccines (LAIV) are 6:2 reassortant viruses containing the HA and NA gene segme...

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Detalles Bibliográficos
Autores principales: Shcherbik, Svetlana, Pearce, Nicholas, Balish, Amanda, Jones, Joyce, Thor, Sharmi, Davis, Charles Todd, Pearce, Melissa, Tumpey, Terrence, Cureton, David, Chen, Li-Mei, Villanueva, Julie, Bousse, Tatiana L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4583547/
https://www.ncbi.nlm.nih.gov/pubmed/26405798
http://dx.doi.org/10.1371/journal.pone.0138951