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Association of the Functional MICA-129 Polymorphism With the Severity of Chronic Chagas Heart Disease

MICA-129 polymorphism affects the binding affinity of MICA molecules with the NKG2D receptor and influences effector cell function. The genotype met/met was associated with the severity of left ventricular systolic dysfunction (LVSD) in patients with chronic Chagas heart disease, while the val/val g...

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Detalles Bibliográficos
Autores principales: Ayo, Christiane Maria, de Oliveira, Amanda Priscila, Camargo, Ana Vitória da Silveira, Brandão de Mattos, Cinara Cássia, Bestetti, Reinaldo Bulgarelli, de Mattos, Luiz Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4583584/
https://www.ncbi.nlm.nih.gov/pubmed/26129751
http://dx.doi.org/10.1093/cid/civ540