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Gene expression changes of single skeletal muscle fibers in response to modulation of the mitochondrial calcium uniporter (MCU)

The mitochondrial calcium uniporter (MCU) gene codifies for the inner mitochondrial membrane (IMM) channel responsible for mitochondrial Ca(2 +) uptake. Cytosolic Ca(2 +) transients are involved in sarcomere contraction through cycles of release and storage in the sarcoplasmic reticulum. In addition...

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Detalles Bibliográficos
Autores principales: Chemello, Francesco, Mammucari, Cristina, Gherardi, Gaia, Rizzuto, Rosario, Lanfranchi, Gerolamo, Cagnin, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4583640/
https://www.ncbi.nlm.nih.gov/pubmed/26484227
http://dx.doi.org/10.1016/j.gdata.2015.05.023