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Gene expression profiling can predict the fate of HeLa cells exposed to X-ray irradiation with or without protoporphyrin accumulation

Protoporphyrin IX (PpIX) enhances the generation of reactive oxygen species in cells following physicochemical interactions with X-rays. To evaluate the use of porphyrins as radio-sensitizers in radiotherapy, the transcriptomic effects of PpIX and/or X-ray irradiation were investigated in HeLa cells...

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Detalles Bibliográficos
Autores principales: Takahashi, Junko, Misawa, Masaki, Iwahashi, Hitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4583665/
https://www.ncbi.nlm.nih.gov/pubmed/26484254
http://dx.doi.org/10.1016/j.gdata.2015.05.044