Cargando…

Defective erythropoiesis in a mouse model of reduced Fbxo7 expression due to decreased p27 expression

During the final stages of erythropoiesis, lineage-restricted progenitors mature over three to five cell divisions, culminating with withdrawal from the cell cycle and the loss of most organelles, including mitochondria and nuclei. Recent genome-wide association studies in human populations have ass...

Descripción completa

Detalles Bibliográficos
Autores principales: Randle, Suzanne J, Nelson, David E, Patel, Shachi P, Laman, Heike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4583784/
https://www.ncbi.nlm.nih.gov/pubmed/26095538
http://dx.doi.org/10.1002/path.4571