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Defective erythropoiesis in a mouse model of reduced Fbxo7 expression due to decreased p27 expression
During the final stages of erythropoiesis, lineage-restricted progenitors mature over three to five cell divisions, culminating with withdrawal from the cell cycle and the loss of most organelles, including mitochondria and nuclei. Recent genome-wide association studies in human populations have ass...
Autores principales: | Randle, Suzanne J, Nelson, David E, Patel, Shachi P, Laman, Heike |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4583784/ https://www.ncbi.nlm.nih.gov/pubmed/26095538 http://dx.doi.org/10.1002/path.4571 |
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