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New mouse xenograft model modulated by tumor-associated fibroblasts for human multi-drug resistance in cancer

We developed an MDR tumor model that is modulated by tumor-associated fibroblasts. Studies on proliferation of tumor cell lines including paclitaxel-sensitive and resistant cell lines were performed. The expressions of P-gp and α-smooth muscle actin (α-SMA) antigen were evaluated by immunohistochemi...

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Detalles Bibliográficos
Autores principales: MA, YAN, LIN, ZHIQIANG, FALLON, JOHN K., ZHAO, QIANG, LIU, DAN, WANG, YONGJUN, LIU, FENG
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4583831/
https://www.ncbi.nlm.nih.gov/pubmed/26352907
http://dx.doi.org/10.3892/or.2015.4265