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Sequential gemcitabine and tamoxifen treatment enhances apoptosis and blocks transformation in bladder cancer cells

Bladder cancer is a common malignancy for which regional or metastatic disease is identified at diagnosis. The aim of this study was to determine whether tamoxifen (Tam), an estrogen receptor (ER) antagonist, can sensitize bladder cancer cell lines to gemcitabine (Gem) chemotherapy. ERα and ERβ prot...

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Detalles Bibliográficos
Autores principales: TAKEUCHI, HISASHI, MMEJE, CHINEDU O., JINESH, GOODWIN G., TAOKA, RIKIYA, KAMAT, ASHISH M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4583834/
https://www.ncbi.nlm.nih.gov/pubmed/26323344
http://dx.doi.org/10.3892/or.2015.4220