Cargando…

Sequential gemcitabine and tamoxifen treatment enhances apoptosis and blocks transformation in bladder cancer cells

Bladder cancer is a common malignancy for which regional or metastatic disease is identified at diagnosis. The aim of this study was to determine whether tamoxifen (Tam), an estrogen receptor (ER) antagonist, can sensitize bladder cancer cell lines to gemcitabine (Gem) chemotherapy. ERα and ERβ prot...

Descripción completa

Detalles Bibliográficos
Autores principales:	TAKEUCHI, HISASHI, MMEJE, CHINEDU O., JINESH, GOODWIN G., TAOKA, RIKIYA, KAMAT, ASHISH M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2015
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4583834/ https://www.ncbi.nlm.nih.gov/pubmed/26323344 http://dx.doi.org/10.3892/or.2015.4220

Ejemplares similares

Novel PKC-ζ to p47(phox) interaction is necessary for transformation from blebbishields
por: Jinesh, Goodwin G., et al.
Publicado: (2016)

Surface PD-L1, E-cadherin, CD24, and VEGFR2 as markers of epithelial cancer stem cells associated with rapid tumorigenesis
por: Jinesh, Goodwin G., et al.
Publicado: (2017)

Redirecting neutrophils against bladder cancer cells by BCG and Smac mimetic combination
por: Jinesh G., Goodwin, et al.
Publicado: (2012)

RalBP1 and p19-VHL play an oncogenic role, and p30-VHL plays a tumor suppressor role during the blebbishield emergency program
por: Jinesh, Goodwin G, et al.
Publicado: (2017)

Genetic variants in the inflammation pathway as predictors of recurrence and progression in non-muscle invasive bladder cancer treated with Bacillus Calmette–Guérin
por: Williams, Stephen B., et al.
Publicado: (2017)

Knockdown of RRM1 with Adenoviral shRNA Vectors to Inhibit Tumor Cell Viability and Increase Chemotherapeutic Sensitivity to Gemcitabine in Bladder Cancer Cells
por: Zhang, Xia, et al.
Publicado: (2021)

Targeting K-Ras and apoptosis-driven cellular transformation in cancer
por: Godwin, Isha, et al.
Publicado: (2021)

Mitochondrial oligomers boost glycolysis in cancer stem cells to facilitate blebbishield-mediated transformation after apoptosis
por: Jinesh, GG, et al.
Publicado: (2016)

Sequential Intravesical Gemcitabine and Docetaxel for the Salvage Treatment of Non-Muscle Invasive Bladder Cancer
por: Steinberg, Ryan L., et al.
Publicado: (2015)

Oncological Outcomes of Sequential Intravesical Gemcitabine and Docetaxel in Patients with Non-Muscle Invasive Bladder Cancer
por: Milbar, Niv, et al.
Publicado: (2017)

Bladder cancer: 2017 and beyond
por: Kamat, Ashish M.
Publicado: (2017)

Genetic Variations in the Transforming Growth Factor Beta Pathway as Predictors of Bladder Cancer Risk
por: Wei, Hua, et al.
Publicado: (2012)

The influence of asymptomatic inflammatory prostatitis on the onset and progression of lower urinary tract symptoms in men with histologic benign prostatic hyperplasia
por: Taoka, Rikiya, et al.
Publicado: (2017)

Bladder Cancer Guidelines: Let Not the Cure Be Worse than the Disease
por: Kamat, Ashish M.
Publicado: (2021)

Successful treatment of metastatic bladder cancer by gemcitabine‐cisplatin re‐challenge after pembrolizumab
por: Arai, Takayuki, et al.
Publicado: (2021)

Comparison between whole mount tissue preparations and virtual tissue microarray samples for measuring Ki-67 and apoptosis indices in human bladder cancer: A cross-sectional study
por: Oshiro, Hisashi, et al.
Publicado: (2016)

Endocytosis and serpentine filopodia drive blebbishield-mediated resurrection of apoptotic cancer stem cells
por: Jinesh, G G, et al.
Publicado: (2016)

In vitro synergistic cytotoxicity of gemcitabine and pemetrexed and pharmacogenetic evaluation of response to gemcitabine in bladder cancer patients
por: Mey, V, et al.
Publicado: (2006)

Advances in risk stratification of bladder cancer to guide personalized medicine
por: Matulay, Justin T., et al.
Publicado: (2018)

Efficacy and toxicity of intravesical Bacillus Calmette-Guérin therapy in elderly patients with non-muscle-invasive bladder cancer
por: Matsuoka, Yuki, et al.
Publicado: (2021)

Exposing the deadly dark side of apoptotic cancer stem cells
por: Jinesh, Goodwin G.
Publicado: (2017)

Comparison of Sequential Intravesical Gemcitabine and Docetaxel vs Bacillus Calmette-Guérin for the Treatment of Patients With High-Risk Non–Muscle-Invasive Bladder Cancer
por: McElree, Ian M., et al.
Publicado: (2023)

Influence of Tamoxifen‐Medroxyprogesterone Sequential Therapy on Estrogen and Progesterone Receptor Contents of Breast Cancer
por: Noguchi, Shinzaburo, et al.
Publicado: (1989)

Antitumor Effects of Orally Administered Rare Sugar D-Allose in Bladder Cancer
por: Tohi, Yoichiro, et al.
Publicado: (2022)

Tamoxifen Induces Apoptosis of Leishmania major Promastigotes in Vitro
por: Doroodgar, Masoud, et al.
Publicado: (2016)

Dasatinib enhances tumor growth in gemcitabine-resistant orthotopic bladder cancer xenografts
por: Vallo, Stefan, et al.
Publicado: (2016)

Sequential therapy for pancreatic cancer by losartan- and gemcitabine-loaded magnetic mesoporous spheres
por: Li, Yanjun, et al.
Publicado: (2019)

Bladder exstrophy in adulthood
por: Nerli, R. B., et al.
Publicado: (2008)

Role of gemcitabine and cisplatin as neoadjuvant chemotherapy in muscle invasive bladder cancer: Experience over the last decade
por: Goel, Sunny, et al.
Publicado: (2019)

Blocking for Sequential Political Experiments
por: Moore, Ryan T., et al.
Publicado: (2013)

Impact of Posterior Urethral Plate Repair on Continence Following Robot-Assisted Laparoscopic Radical Prostatectomy
por: Kim, Isaac Yi, et al.
Publicado: (2010)

Tumorigenic Effects of Tamoxifen on the Female Genital Tract
por: Nasu, Kaei, et al.
Publicado: (2008)

HMGB1-mediated autophagy attenuates gemcitabine-induced apoptosis in bladder cancer cells involving JNK and ERK activation
por: Yin, Hubin, et al.
Publicado: (2017)

Niban apoptosis regulator 1 promotes gemcitabine resistance by activating the focal adhesion kinase signaling pathway in bladder cancer
por: Tong, Shiyu, et al.
Publicado: (2022)

Relationship between tamoxifen-induced transforming growth factor beta 1 expression, cytostasis and apoptosis in human breast cancer cells.
por: Perry, R. R., et al.
Publicado: (1995)

Modulation of transforming growth factor beta expression and induction of apoptosis by tamoxifen in ER positive and ER negative breast cancer cells.
por: Benson, J. R., et al.
Publicado: (1996)

Pros and cons of radical cystectomy in the treatment of T1G3 bladder cancer
por: Agarwal, Piyus K., et al.
Publicado: (2008)

P300 inhibition enhances gemcitabine-induced apoptosis of pancreatic cancer
por: Ono, Hiroaki, et al.
Publicado: (2016)

Ellagic Acid Resensitizes Gemcitabine-Resistant Bladder Cancer Cells by Inhibiting Epithelial-Mesenchymal Transition and Gemcitabine Transporters
por: Wu, Ying-Si, et al.
Publicado: (2021)

Efficacy, Safety, and Prognosis of Sequential Therapy with Tamoxifen and Letrozole versus Letrozole Monotherapy for Breast Carcinoma
por: Lu, Xinli, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_kaaaknh72047qcftmd5961na8b